The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28650658 |
54 |
Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization.![EBI](/images/logo_chembl.png) |
Shandong University |
27584694 |
103 |
Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.![EBI](/images/logo_chembl.png) |
Icahn School of Medicine At Mount Sinai |
26824386 |
41 |
Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.![EBI](/images/logo_chembl.png) |
University of Toronto |
26101569 |
66 |
Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.![EBI](/images/logo_chembl.png) |
Epizyme |
25559100 |
25 |
Exploration of cyanine compounds as selective inhibitors of protein arginine methyltransferases: synthesis and biological evaluation.![EBI](/images/logo_chembl.png) |
The University of Georgia |
27390919 |
96 |
Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.![EBI](/images/logo_chembl.png) |
University of Toronto |
30605830 |
102 |
Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation.![EBI](/images/logo_chembl.png) |
Shanghai Institute of Materia Medica |
31117515 |
60 |
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia.![EBI](/images/logo_chembl.png) |
Chinese Academy of Sciences |
32367723 |
22 |
Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor.![EBI](/images/logo_chembl.png) |
Icahn School of Medicine At Mount Sinai |
29019697 |
24 |
Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.![EBI](/images/logo_chembl.png) |
Zhejiang Sci-Tech University |