The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
15878277 |
42 |
Synthesis and phosphodiesterase 5 inhibitory activity of novel pyrido[1,2-e]purin-4(3H)-one derivatives. |
Chinese Academy of Sciences |
12824030 |
67 |
1,7- and 2,7-naphthyridine derivatives as potent and highly specific PDE5 inhibitors. |
Tanabe Seiyaku |
21988093 |
316 |
Highly potent, selective, and orally active phosphodiesterase 10A inhibitors. |
Pfizer |
19906530 |
22 |
Discovery of potent, selective, and orally bioavailable PDE5 inhibitor: Methyl-4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-ylmethylcarbamate (CKD 533). |
Chong Kun Dang Research Institute |
15837329 |
37 |
New pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors. |
RhôNe-Poulenc Rorer |
15080987 |
20 |
Synthesis and phosphodiesterase 5 inhibitory activity of new sildenafil analogues containing a phosphonate group in the 5(')-sulfonamide moiety of phenyl ring. |
Ewha Womans University |
14521415 |
44 |
The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues. |
Glaxosmithkline |
12182866 |
83 |
8-Aryl xanthines potent inhibitors of phosphodiesterase 5. |
Novartis Horsham Research Centre |
29718668 |
27 |
Discovery of Potent and Selective Periphery-Restricted Quinazoline Inhibitors of the Cyclic Nucleotide Phosphodiesterase PDE1. |
Pfizer |