The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28302506 |
28 |
Xanthine oxidase inhibitory activity of nicotino/isonicotinohydrazides: A systematic approach from in vitro, in silico to in vivo studies. |
University of Karachi |
| 27614410 |
27 |
Synthesis and evaluation of xanthine oxidase inhibitory and antioxidant activities of 2-arylbenzo[b]furan derivatives based on salvianolic acid C. |
China Pharmaceutical University |
| 28340987 |
10 |
Discovery of novel curcumin derivatives targeting xanthine oxidase and urate transporter 1 as anti-hyperuricemic agents. |
Soochow University |
| 27162124 |
2 |
On the vasoprotective mechanisms underlying novelß-phosphorylated nitrones: Focus on free radical characterization, scavenging and NO-donation in a biological model of oxidative stress. |
Aix-Marseille Universit£ |
| 26762836 |
16 |
Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers. |
Northern Kentucky University |
| 26712096 |
3 |
9-Benzoyl 9-deazaguanines as potent xanthine oxidase inhibitors. |
Universidade Estadual De Campinas |
| 26096677 |
2 |
An oxidative coupling product of luteolin with cysteine ester and its enhanced inhibitory activity for xanthine oxidase. |
Osaka City University |
| 26022844 |
20 |
Discovery of xanthine oxidase inhibitors and/ora-glucosidase inhibitors by carboxyalkyl derivatization based on the flavonoid of apigenin. |
Beijing Institute of Pharmacology & Toxicology |
| 25019478 |
13 |
Flavones: an important scaffold for medicinal chemistry. |
Punjabi University |
| 321782 |
9 |
A manual method for applying the Hansch approach to drug design. |
TBA |
| 24508129 |
45 |
HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase. |
Astrazeneca |
| 23122864 |
19 |
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia. |
Piramal Healthcare |
| 21174408 |
13 |
Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp. |
Chulabhorn Institute |
| 9461655 |
33 |
Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers. |
University of Antwerp |
| 15730241 |
12 |
Bioactive constituents from Boswellia papyrifera. |
University of Karachi |
| 11678667 |
1 |
Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa. |
Universit£ |
| 17346963 |
12 |
Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill). |
Institute For Natural Product Research and Infection Biology |
| 12873513 |
8 |
Novel 3-O-acyl mesquitol analogues as free-radical scavengers and enzyme inhibitors: synthesis, biological evaluation and structure-activity relationship. |
Institute of Chemical Technology |
| 22041175 |
74 |
Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors. |
Genkyotex |
| 21345544 |
13 |
Antioxidant xanthone derivatives induce cell cycle arrest and apoptosis and enhance cell death induced by cisplatin in NTUB1 cells associated with ROS. |
Kaohsiung Medical University |
| 20942471 |
79 |
First in class, potent, and orally bioavailable NADPH oxidase isoform 4 (Nox4) inhibitors for the treatment of idiopathic pulmonary fibrosis. |
Genkyotex |
| 20384317 |
1 |
Glutarimide alkaloids and a terpenoid benzoquinone from Cordia globifera. |
Chulabhorn Research Institute |
| 19476336 |
4 |
Chemical constituents from the aerial parts of Artemisia minor. |
Chinese Academy of Sciences |
| 19800788 |
1 |
Insights into the inhibition of xanthine oxidase by curcumin. |
Shandong University of Technology |
| 19362850 |
3 |
Preparation of two sets of 5,6,7-trioxygenated dihydroflavonol derivatives as free radical scavengers and neuronal cell protectors to oxidative damage. |
Pharmacy School of Wenzhou Medical College |
| 18722771 |
14 |
ortho-dihydroxyisoflavone derivatives from aged Doenjang (Korean fermented soypaste) and its radical scavenging activity. |
Amorepacific |
| 18606546 |
3 |
Synthesis and cytotoxic, anti-inflammatory, and anti-oxidant activities of 2',5'-dialkoxylchalcones as cancer chemopreventive agents. |
Kaohsiung Medical University |
| 18512985 |
3 |
Phloroglucinols with antioxidant activity and xanthonolignoids from the heartwood of Hypericum geminiflorum. |
Kaohsiung Medical University |
| 17706325 |
1 |
Schiff base transition metal complexes as novel inhibitors of xanthine oxidase. |
Nanjing University |
| 17692432 |
18 |
Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors. |
Universidade Do Minho |
| 16872152 |
5 |
An apigenin-derived xanthine oxidase inhibitor from Palhinhaea cernua. |
Nanjing University |
| 16309309 |
6 |
Free-radical-scavenging and xanthine oxidase inhibitory constituents from Stereospermum personatum. |
Institute of Chemical Technology |
| 16038560 |
2 |
Structural revision of aspernigrin A, reisolated from Cladosporium herbarum IFB-E002. |
Nanjing University |
| 12444671 |
10 |
Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata. |
Università |
| 10425142 |
3 |
New guaianolides and xanthine oxidase inhibitory flavonols from ajania fruticulosa |
Nanjing University |
| 17379526 |
13 |
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors. |
Institute of Biological Chemistry and The Genomics Research Center |
| 17316915 |
7 |
Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition. |
Università |
| 31924495 |
22 |
Development of novel NLRP3-XOD dual inhibitors for the treatment of gout. |
Soochow University |
| 30769179 |
24 |
Pharmacological urate-lowering approaches in chronic kidney disease. |
West China Hospital of Sichuan University |
| 30630716 |
5 |
Discovery of 2-phenylthiazole-4-carboxylic acid, a novel and potent scaffold as xanthine oxidase inhibitors. |
Guangzhou General Pharmaceutical Research Institute |
| 8691450 |
49 |
Synthesis and biological evaluation of new imidazole, pyrimidine, and purine derivatives and analogs as inhibitors of xanthine oxidase. |
Università |
| 26487910 |
50 |
Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase. |
Emory University |
| 25060641 |
8 |
X-ray crystal structure of a xanthine oxidase complex with the flavonoid inhibitor quercetin. |
University of California |
| 23851116 |
13 |
Synthesis and biological evaluation of pyrazolo[4,3-d]pyrimidine analogues. |
Sichuan University |
| 22677314 |
14 |
Xanthine oxidase inhibitory activity of constituents of Cinnamomum cassia twigs. |
National Institute of Medicinal Materials |
| 30015075 |
5 |
Current progress on antioxidants incorporating the pyrazole core. |
University of Aveiro |
| 29472126 |
36 |
Development of benzoxazole deoxybenzoin oxime and acyloxylamine derivatives targeting innate immune sensors and xanthine oxidase for treatment of gout. |
Soochow University |
| 29920453 |
19 |
Design, synthesis and bioevaluation of 2-mercapto-6-phenylpyrimidine-4-carboxylic acid derivatives as potent xanthine oxidase inhibitors. |
Shenyang Pharmaceutical University |
| 29223098 |
5 |
Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents. |
University of Beira Interior |
| 28972762 |
2 |
Berchemiosides A-C, 2-Acetoxy-?-phenylpentaene Fatty Acid Triglycosides from the Unripe Fruits of Berchemia berchemiifolia. |
Seoul National University |
| 28478180 |
69 |
Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity. |
University of Nis |
| 28511908 |
13 |
Potential anti-gout constituents as xanthine oxidase inhibitor from the fruits of Stauntonia brachyanthera. |
Shenyang Pharmaceutical University |
| 14561090 |
21 |
Design and synthesis of 4-azaindoles as inhibitors of p38 MAP kinase. |
Roche Palo Alto |
| 17276063 |
38 |
Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit. |
Abbott Laboratories |
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