The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24654918 |
19 |
Pharmacophoric modifications lead to superpotentavß3 integrin ligands with suppresseda5ß1 activity. |
Technische Universit£T M£Nchen |
23362923 |
59 |
Biselectivity of isoDGR peptides for fibronectin binding integrin subtypesa5ß1 andavß6: conformational control through flanking amino acids. |
Technische Universit£T M£Nchen |
17399986 |
114 |
R-isomers of Arg-Gly-Asp (RGD) mimics as potent alphavbeta3 inhibitors. |
Pfizer |
17387018 |
74 |
Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective alphavbeta3 inhibitor: design, synthesis, and optimization. |
Pfizer |
16621534 |
87 |
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists. |
Pfizer |
16303301 |
44 |
Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic properties. |
Pfizer |
16298127 |
80 |
Convergent, parallel synthesis of a series of beta-substituted 1,2,4-oxadiazole butanoic acids as potent and selective alpha(v)beta3 receptor antagonists. |
Pfizer |
11855984 |
102 |
Nanomolar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins. |
Merck |
32094009 |
36 |
Novel cilengitide-based cyclic RGD peptides as ?v? |
Division of Organic Chemistry Csir-National Chemical Laboratory (Ncl) |
30657681 |
262 |
Selective Targeting of Integrin ?v?8 by a Highly Active Cyclic Peptide. |
Technische Universit£T M£Nchen |
31381331 |
70 |
Profile of a Highly Selective Quaternized Pyrrolidine Betaine ? |
Glaxosmithkline Medicines Research Centre |
31497959 |
48 |
Discovery of an Orally Bioavailable Pan ?v Integrin Inhibitor for Idiopathic Pulmonary Fibrosis. |
Glaxosmithkline Medicines Research Centre |
24568695 |
76 |
Strategies to inhibit tumor associated integrin receptors: rationale for dual and multi-antagonists. |
University of Bradford |
25408832 |
152 |
Structure Activity Relationships of ?v Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents. |
University of Nottingham |
30215258 |
228 |
Discovery of ( S)-3-(3-(3,5-Dimethyl-1 H-pyrazol-1-yl)phenyl)-4-(( R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic ? |
University of Strathclyde |