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13 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
32143887 58 Design and synthesis of novel 2-arylbenzimidazoles as selective mutant isocitrate dehydrogenase 2 R140Q inhibitors.EBI Shandong Provincial Hospital Affiliated To Shandong University
31199148 148 Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors.EBI Forma Therapeutics
32071674 30 Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma.EBI Agios Pharmaceuticals
30600148 65 Synthesis and biological evaluation of 3-aryl-4-indolyl-maleimides as potent mutant isocitrate dehydrogenase-1 inhibitors.EBI Zhejiang University
31971798 40 Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor.EBI Forma Therapeutics
29847930 142 Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective.EBI China Pharmaceutical University
29079473 62 Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors.EBI Shanghai Haihe
29057059 82 Lucky Switcheroo: Dramatic Potency and Selectivity Improvement of Imidazoline Inhibitors of Human Carbonic Anhydrase VII.EBI Saint Petersburg State University
17293454 7 An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists.BDB The Scripps Research Institute