34 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28111141	58	The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics.	Merck
28105264	6	Potential of Renal Outer Medullary Potassium (ROMK) Channel as Treatments for Hypertension and Heart Failure.	Therachem Research Medilab (India)
27839686	65	Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffold.	Merck Research Laboratories
27190590	11	Inhibitors of Renal Outer Medullary Potassium Channel.	Temple University
27017115	77	Differentiation of ROMK potency from hERG potency in the phenacetyl piperazine series through heterocycle incorporation.	Merck Research Laboratories
26288678	12	Inhibitors of the Renal Outer Medullary Potassium Channel.	Temple University
26191360	99	Discovery of a Potent and Selective ROMK Inhibitor with Pharmacokinetic Properties Suitable for Preclinical Evaluation.	Merck Research Laboratories
24075732	43	Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one.	Merck Research Laboratories
24900480	75	Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics.	TBA
27437080	96	Discovery of MK-7145, an Oral Small Molecule ROMK Inhibitor for the Treatment of Hypertension and Heart Failure.	Merck Research Laboratories
31034224	24	Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics.	University of Nebraska Medical Center
29456800	47	Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors.	Pfizer
28431879	123	Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophores.	Merck
26833890	18	Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease.	Yogi Vemana University
26469307	7	Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b.	University of Leipzig
17620441	5	Novel antagonists of the thioesterase domain of human fatty acid synthase.	Burnham Institute For Medical Research
11196150	3	Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro.	Janssen Research Foundation
14592500	29	Novel HIV-1 protease inhibitors active against multiple PI-resistant viral strains: coadministration with indinavir.	Merck Research Laboratories