The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27455395 |
66 |
Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor Complex. |
Bristol-Myers Squibb R & D |
26827162 |
6 |
Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors. |
University Of Namur |
26704266 |
80 |
Novel phenylalanine derived diamides as Factor XIa inhibitors. |
Bristol-Myers Squibb |
26005539 |
23 |
Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety. |
Bristol-Myers Squibb |
25405503 |
109 |
Phenylimidazoles as potent and selective inhibitors of coagulation factor XIa with in vivo antithrombotic activity. |
Bristol-Myers Squibb |
24461292 |
14 |
Heterocyclic core analogs of a direct thrombin inhibitor. |
Merck Research Laboratories |
23586812 |
38 |
Development of a selective peptide macrocycle inhibitor of coagulation factor XII toward the generation of a safe antithrombotic therapy. |
Ecole Polytechnique F�D�Rale De Lausanne Epfl |
23294255 |
114 |
Development of new cyclic plasmin inhibitors with excellent potency and selectivity. |
Philipps University Marburg |
22770607 |
54 |
Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold. |
Virginia Commonwealth University |
18053726 |
364 |
Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality. |
Johnson & Johnson Pharmaceutical Research & Development |
9301673 |
234 |
Synthesis and structure-activity relationships of potent thrombin inhibitors: piperazides of 3-amidinophenylalanine. |
Klinikum Der Friedrich-Schiller-Universit£T Jena |
18674905 |
58 |
Factor VIIa inhibitors: target hopping in the serine protease family using X-ray structure determination. |
Chugai Pharmaceutical |
| 18 |
Novel multi-targeted agents for Alzheimer's disease: Synthesis, biological evaluation, and molecular modeling of novel 2-[4-(4-substitutedpiperazin-1-yl)phenyl]benzimidazoles |
Hacettepe University |
11093801 |
7 |
Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. |
University Of California Irvine |
21168763 |
9 |
Natural product-guided discovery of a fungal chitinase inhibitor. |
University Of Dundee |
24058293 |
12 |
Modulation of global low-frequency motions underlies allosteric regulation: demonstration in CRP/FNR family transcription factors. |
Durham University |