The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
23688699 |
3 |
Evaluation of adenine as scaffold for the development of novel P2X3 receptor antagonists. |
University of Camerino |
16250663 |
8 |
Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency. |
University of Bonn |
20045645 |
66 |
Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist. |
Roche Palo Alto |
22370269 |
44 |
Discovery of P2X3 selective antagonists for the treatment of chronic pain. |
Astrazeneca |
21207957 |
163 |
Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor. |
University of Bonn |
12213051 |
207 |
Purine and pyrimidine (P2) receptors as drug targets. |
National Institute of Diabetes |
19231180 |
81 |
Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain. |
Roche Palo Alto |
19231178 |
61 |
Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain. |
Roche Palo Alto |
11462975 |
50 |
Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. |
National Institute of Diabetes and Digestive and Kidney Diseases |
9632352 |
7 |
A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors. |
National Institute of Diabetes and Digestive and Kidney Diseases |
12798321 |
26 |
Nicotinyl aspartyl ketones as inhibitors of caspase-3. |
Merck Frosst Canada |
16570918 |
49 |
Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis. |
Saarland University |