The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 27816515 |
143 |
Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors. |
Merck |
| 27727125 |
24 |
Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators. |
Pfizer |
| 27490827 |
24 |
Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy. |
Pfizer |
| 24900695 |
19 |
Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators. |
Chinese Academy of Sciences |
| 23550937 |
72 |
Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties. |
Emory University |
| 22795331 |
51 |
Pyrimidinopyrimidine inhibitors of ketohexokinase: exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket. |
Janssen Pharmaceutical Companies of Johnson & Johnson |
| 24900346 |
90 |
Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site. |
TBA |
| 31757666 |
314 |
Discovery and optimization of heteroaryl piperazines as potent and selective PI3K? inhibitors. |
Merck |
| 31744674 |
23 |
Design, synthesis and biological evaluation of mogrol derivatives as a novel class of AMPK?2?1?1 activators. |
Nanjing University of Chinese Medicine |
| 27491711 |
422 |
Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. |
Merck And |
| 30986571 |
66 |
Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies. |
Zhejiang University |
| 31358465 |
9 |
Towards multi-target antidiabetic agents: Discovery of biphenyl-benzimidazole conjugates as AMPK activators. |
Volgograd State Medical University |
| 31526603 |
379 |
Structure-based rational design of staurosporine-based fluorescent probe with broad-ranging kinase affinity for kinase panel application. |
Takeda Pharmaceutical |
| 29211480 |
64 |
Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy. |
China Pharmaceutical University |
| 26510622 |
2 |
Pharmacological Targeting of AMP-Activated Protein Kinase and Opportunities for Computer-Aided Drug Design. |
Maastricht University |
| 30036059 |
40 |
Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK). |
Pfizer |
| 29620890 |
25 |
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations. |
Glaxosmithkline |
| 28345906 |
9 |
Malonylginsenosides with Potential Antidiabetic Activities from the Flower Buds of Panax ginseng. |
Chinese Academy of Sciences |
| 29348809 |
1 |
Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase. |
Merck Research Laboratories |
| 29035567 |
38 |
Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase. |
Metabasis Therapeutics |
| 29466005 |
25 |
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK). |
Pfizer |
| 20020776 |
56 |
In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors. |
Vanderbilt University |
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