The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
25590374 |
23 |
Hupehenols A-E, selective 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD1) inhibitors from Viburnum hupehense. |
Chinese Academy of Sciences |
24294985 |
42 |
Medicinal chemistry of inhibitors of 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD1). |
Astrazeneca |
23747808 |
51 |
Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11ß-HSD1 inhibitors: potential impact in diabetes. |
Chinese Academy of Sciences |
22360639 |
12 |
Cycloartane and friedelane triterpenoids from the leaves of Caloncoba glauca and their evaluation for inhibition of 11ß-hydroxysteroid dehydrogenases. |
Chinese Academy of Sciences |
22440625 |
44 |
Synthesis and evaluation of piperidine urea derivatives as efficacious 11ß-hydroxysteroid dehydrogenase type 1 inhibitors in diabetic ob/ob mice. |
Chinese Academy of Sciences |
19564108 |
48 |
4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice. |
Chinese Academy of Sciences |
18440812 |
113 |
Phenylcyclobutyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I. |
Merck Research Laboratories |
21334894 |
218 |
Substituted phenyl triazoles as selective inhibitors of 11 β-Hydroxysteroid Dehydrogenase Type 1. |
Merck |
21421311 |
135 |
Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome. |
Merck Research Laboratories |
18440811 |
207 |
4-Methyl-5-phenyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I. |
Merck Research Laboratories |
17201418 |
105 |
Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors. |
Abbott Laboratories |
17070044 |
102 |
Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors. |
Abbott Laboratories |
16996734 |
93 |
Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction. |
Abbott Laboratories |
16931002 |
73 |
Discovery of orally active butyrolactam 11beta-HSD1 inhibitors. |
Abbott Laboratories |
16899366 |
85 |
Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors. |
Abbott Laboratories |
16890427 |
81 |
Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements. |
Abbott Laboratories |
16185866 |
53 |
Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11beta-HSD1: novel therapeutic agents for the treatment of metabolic syndrome. |
Merck |
28458137 |
25 |
Synthesis of selective 11?-HSD1 inhibitors based on dammarane scaffold. |
Chinese Academy of Sciences |
28537398 |
114 |
Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11?-Hydroxysteroid Dehydrogenase Type 1 Inhibitor. |
Bristol-Myers Squibb |
20187655 |
12 |
Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors. |
Academia Sinica |