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20 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
25590374 23 Hupehenols A-E, selective 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD1) inhibitors from Viburnum hupehense.EBI Chinese Academy of Sciences
24294985 42 Medicinal chemistry of inhibitors of 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD1).EBI Astrazeneca
23747808 51 Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11ß-HSD1 inhibitors: potential impact in diabetes.EBI Chinese Academy of Sciences
22360639 12 Cycloartane and friedelane triterpenoids from the leaves of Caloncoba glauca and their evaluation for inhibition of 11ß-hydroxysteroid dehydrogenases.EBI Chinese Academy of Sciences
22440625 44 Synthesis and evaluation of piperidine urea derivatives as efficacious 11ß-hydroxysteroid dehydrogenase type 1 inhibitors in diabetic ob/ob mice.EBI Chinese Academy of Sciences
19564108 48 4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice.EBI Chinese Academy of Sciences
18440812 113 Phenylcyclobutyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.EBI Merck Research Laboratories
21334894 218 Substituted phenyl triazoles as selective inhibitors of 11 β-Hydroxysteroid Dehydrogenase Type 1.EBI Merck
21421311 135 Bicyclo[2.2.2]octyltriazole inhibitors of 11β-hydoxysteroid dehydrogenase type 1. Pharmacological agents for the treatment of metabolic syndrome.EBI Merck Research Laboratories
18440811 207 4-Methyl-5-phenyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.EBI Merck Research Laboratories
17201418 105 Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.EBI Abbott Laboratories
17070044 102 Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.EBI Abbott Laboratories
16996734 93 Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction.EBI Abbott Laboratories
16931002 73 Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.EBI Abbott Laboratories
16899366 85 Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.EBI Abbott Laboratories
16890427 81 Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements.EBI Abbott Laboratories
16185866 53 Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11beta-HSD1: novel therapeutic agents for the treatment of metabolic syndrome.EBI Merck
28458137 25 Synthesis of selective 11?-HSD1 inhibitors based on dammarane scaffold.EBI Chinese Academy of Sciences
28537398 114 Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11?-Hydroxysteroid Dehydrogenase Type 1 Inhibitor.EBI Bristol-Myers Squibb
20187655 12 Development of GlcNAc-inspired iminocyclitiols as potent and selective N-acetyl-beta-hexosaminidase inhibitors.BDB Academia Sinica