The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27441737 |
5 |
Myrsinane, Premyrsinane, and Cyclomyrsinane Diterpenes from Euphorbia falcata as Potassium Ion Channel Inhibitors with Selective G Protein-Activated Inwardly Rectifying Ion Channel (GIRK) Blocking Effects. |
Rytmion |
23916258 |
54 |
Discovery and SAR of a novel series of GIRK1/2 and GIRK1/4 activators. |
Vanderbilt University |
23838260 |
86 |
Discovery of 'molecular switches' within a GIRK activator scaffold that afford selective GIRK inhibitors. |
Northwest Agriculture & Forestry University |
30718161 |
98 |
Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators. |
University of Nebraska Medical Center |
30879840 |
36 |
Potassium channel blocking 1,2-bis(aryl)ethane-1,2-diamines active as antiarrhythmic agents. |
Astrazeneca |
31034224 |
24 |
Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics. |
University of Nebraska Medical Center |
25264075 |
112 |
Discovery of potent and selective GIRK1/2 modulators via 'molecular switches' within a series of 1-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)ureas. |
Northwest A&F University |
30411614 |
7 |
Diterpenoids from Euphorbia dulcis with Potassium Ion Channel Inhibitory Activity with Selective G Protein-Activated Inwardly Rectifying Ion Channel (GIRK) Blocking Effect. |
Rytmion |