The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 27769036 |
16 |
Green fluorescent protein chromophore derivatives as a new class of aldose reductase inhibitors. |
Toho University |
| 27140653 |
2 |
Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract. |
University of Colorado |
| 25890697 |
6 |
Thiazolidine-2,4-dione derivatives: programmed chemical weapons for key protein targets of various pathological conditions. |
Punjabi University |
| 25695864 |
35 |
Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold. |
Slovak Academy of Sciences |
| 25375908 |
9 |
Targeting aldose reductase for the treatment of diabetes complications and inflammatory diseases: new insights and future directions. |
Universit£ |
| 25152999 |
9 |
20(S)-Ginsenoside Rh2 as aldose reductase inhibitor from Panax ginseng. |
Kyushu University |
| 24071447 |
39 |
Synthesis and structure-activity relationship of 2-phenyliminochromene derivatives as inhibitors for aldo-keto reductase (AKR) 1B10. |
Gifu Pharmaceutical University |
| 23683835 |
21 |
Synthesis of organic nitrates of luteolin as a novel class of potent aldose reductase inhibitors. |
Xiangtan University |
| 21413808 |
170 |
Synopsis of some recent tactical application of bioisosteres in drug design. |
Bristol-Myers Squibb Pharmaceutical Research and Development |
| 21561086 |
21 |
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid. |
Gifu Pharmaceutical University |
| 22263837 |
262 |
Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17ß-hydroxysteroid dehydrogenase) based on N-phenyl-aminobenzoates and their structure-activity relationships. |
University of Pennsylvania |
| 24900359 |
31 |
Optimization of the Central Core of Indolinone-Acetic Acid-Based CRTH2 (DP2) Receptor Antagonists. |
TBA |
| 18492610 |
9 |
Synthesis, induced-fit docking investigations, and in vitro aldose reductase inhibitory activity of non-carboxylic acid containing 2,4-thiazolidinedione derivatives. |
Universit£ |
| 18165015 |
18 |
Inhibition of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) by aldose reductase inhibitors. |
Monash University |
| 18087047 |
3 |
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10. |
Universitat Aut£Noma De Barcelona |
| 12540241 |
5 |
Substituted pyrrol-1-ylacetic acids that combine aldose reductase enzyme inhibitory activity and ability to prevent the nonenzymatic irreversible modification of proteins from monosaccharides. |
Aristotle University of Thessaloniki |
| 10737739 |
11 |
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants. |
National Eye Institute |
| 8027986 |
30 |
Novel spirosuccinimide aldose reductase inhibitors derived from isoquinoline-1,3-diones: 2-[(4-bromo-2-fluorophenyl)methyl]-6- fluorospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and congeners. 1. |
Wyeth-Ayerst Research |
| 1613744 |
69 |
Hydantoin bioisosteres. In vivo active spiro hydroxy acetic acid aldose reductase inhibitors. |
Pfizer |
| 1900532 |
44 |
A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners. |
Pfizer |
| 2113948 |
11 |
Spiro hydantoin aldose reductase inhibitors derived from 8-aza-4-chromanones. |
Pfizer |
| 3121857 |
128 |
Spiro hydantoin aldose reductase inhibitors. |
Pfizer |
| 22104435 |
54 |
Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-ß-carbolin-9-yl)acetic acids as selective inhibitors for AKR1B1. |
University of Toyama |
| 22261024 |
21 |
Construction of an Indonesian herbal constituents database and its use in Random Forest modelling in a search for inhibitors of aldose reductase. |
King'S College London |
| 22236472 |
51 |
Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B10. |
Gifu Pharmaceutical University |
| 22047696 |
17 |
Structure-activity relationships of ganoderma acids from Ganoderma lucidum as aldose reductase inhibitors. |
Sepuluh Nopember Institute of Technology |
| 22037047 |
1 |
(2-Benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid: an aldose reductase inhibitor and antioxidant of zwitterionic nature. |
Slovak Academy of Sciences |
| 21944852 |
79 |
Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists-discovery of AZD1981. |
Astrazeneca R&D Charnwood |
| 21916510 |
167 |
Discovery of potent, selective, and orally bioavailable alkynylphenoxyacetic acid CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases. |
Merck Serono |
| 19250825 |
4 |
Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. |
The Institute For Diabetes Discovery |
| 21256748 |
8 |
Furoxan nitric oxide donor coupled chrysin derivatives: synthesis and vasculoprotection. |
Central South University |
| 21129963 |
23 |
In vitro evaluation of 5-arylidene-2-thioxo-4-thiazolidinones active as aldose reductase inhibitors. |
University of Messina |
| 20805028 |
32 |
6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2. |
University of Toyama |
| 20304656 |
31 |
Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10. |
Gifu Pharmaceutical University |
| 20071057 |
4 |
Evaluation of aldose reductase inhibition and docking studies of 6'-nitro and 6',6''-dinitrorosmarinic acids. |
National Hellenic Research Foundation |
| 20189816 |
8 |
Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole. |
Aristotle University of Thessaloniki |
| 18976928 |
1 |
Inhibition of aldose reductase from cataracted eye lenses by finger millet (Eleusine coracana) polyphenols. |
Central Food Technological Research Institute |
| 17870536 |
28 |
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors. |
Università |
| 16107153 |
10 |
Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. |
Monash University (Parkville Campus) |
| 15317464 |
4 |
High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor. |
Monash University (Parkville Campus) |
| 14613323 |
10 |
Synthesis, activity, and molecular modeling studies of novel human aldose reductase inhibitors based on a marine natural product. |
Instituto Biomar |
| 31744675 |
27 |
Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay. |
Kyushu University |
| 10882376 |
7 |
A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography. |
Rational Drug Design Laboratories |
| 31221611 |
20 |
Synthesis and molecular modeling of novel non-sulfonylureas as hypoglycemic agents and selective ALR2 inhibitors. |
Suez Canal University |
| 30818176 |
64 |
Synthesis of new arylsulfonylspiroimidazolidine-2',4'-diones and study of their effect on stimulation of insulin release from MIN6 cell line, inhibition of human aldose reductase, sorbitol accumulations in various tissues and oxidative stress. |
Quaid-I-Azam University |
| 31820975 |
19 |
Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity. |
Comenius University In Bratislava |
| 31401008 |
34 |
Synthesis and biological activity of structurally diverse phthalazine derivatives: A systematic review. |
Y. B. Chavan College of Pharmacy |
| 30342956 |
44 |
An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications. |
University of Messina |
| 26529431 |
16 |
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment. |
University of Hradec Kralove |
| 24341381 |
2 |
Design of an amide N-glycoside derivative of ?-glucogallin: a stable, potent, and specific inhibitor of aldose reductase. |
University of Colorado Anschutz Medical Campus |
| 6779009 |
1 |
Synthesis and aldose reductase inhibitory activity of 7-sulfamoylxanthone-2-carboxylic acids. |
TBA |
| 10096852 |
4 |
New phenolic and quinone-methide triterpenes from Maytenus amazonica. |
Universidad De La Laguna |
| 9461656 |
1 |
Friedelane triterpenoids from Maytenus macrocarpa. |
Universidad De Laguna |
| 15844965 |
7 |
Structures and aldose reductase inhibitory effects of bromophenols from the red alga Symphyocladia latiuscula. |
Jilin Province Academy of Traditional Chinese Medicine and Materia Medica |
| 3934383 |
6 |
Synthesis, absolute configuration, and conformation of the aldose reductase inhibitor sorbinil. |
TBA |
| 3925146 |
43 |
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications. |
TBA |
| 3097317 |
19 |
Antiinflammatory and aldose reductase inhibitory activity of some tricyclic arylacetic acids. |
TBA |
| 29074349 |
29 |
Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity. |
Slovak Academy of Sciences |
| 2498517 |
31 |
Rotationally restricted mimics of rigid molecules: nonspirocyclic hydantoin aldose reductase inhibitors. |
Pfizer |
| 28759875 |
30 |
An overview of benzo[b]thiophene-based medicinal chemistry. |
Jain University |
| 29589935 |
4 |
Lipophilic Efficiency as an Important Metric in Drug Design. |
Pfizer |
| 1956050 |
18 |
Gossypol and derivatives: a new class of aldose reductase inhibitors. |
University of New Mexico School of Medicine |
| 28802633 |
2 |
1-Acetyl-5-phenyl-1H-pyrrol-3-ylacetate: An aldose reductase inhibitor for the treatment of diabetic nephropathy. |
Shanghai Institute of Pharmaceutical Industry |
| 1899452 |
90 |
Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners. |
Pfizer |
| 1738141 |
64 |
Potent, orally active aldose reductase inhibitors related to zopolrestat: surrogates for benzothiazole side chain. |
Pfizer |
| 1613743 |
29 |
Orally active aldose reductase inhibitors: indazoleacetic, oxopyridazineacetic, and oxopyridopyridazineacetic acid derivatives. |
Pfizer |
| 1597858 |
56 |
Biological activities and quantitative structure-activity relationships of spiro[imidazolidine-4,4'(1'H)-quinazoline]-2,2',5(3'H)-triones as aldose reductase inhibitors. |
Tanabe Seiyaku |
| 28976752 |
51 |
Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells. |
Gifu Pharmaceutical University |
| 28390993 |
46 |
New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study. |
Alexandria University |
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