The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 26218343 |
76 |
Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site. |
Eli Lilly |
| 24755427 |
107 |
The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation. |
Astrazeneca |
| 22917520 |
45 |
Discovery of liver selective non-steroidal glucocorticoid receptor antagonist as novel antidiabetic agents. |
Zydus Research Centre |
| 22465636 |
125 |
Steroidal C-21 heteroaryl thioethers. Part 3: pregn-4-eno-[3,2-c]pyrazole fused A ring modified steroids as selective glucocorticoid receptor modulators (dissociated steroids). |
Merck Research Laboratories |
| 15261266 |
39 |
Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator. |
Abbott Laboratories |
| 15261265 |
38 |
Synthesis, activity, metabolic stability, and pharmacokinetics of glucocorticoid receptor modulator-statin hybrids. |
Abbott Laboratories |
| 8960547 |
19 |
Anti-inflammatory 17beta-thioalkyl-16alpha,17alpha-ketal and -acetal androstanes: a new class of airway selective steroids for the treatment of asthma. |
Rh£Ne-Poulenc Rorer Central Research |
| 1875343 |
7 |
Synthesis and evaluation of antiinflammatory activities of a series of corticosteroid 17 alpha-esters containing a functional group. |
Mitsubishi Kasei |
| 12824023 |
6 |
An evaluation of a C-glucuronide as a liver targeting group: conjugate of a glucocorticoid antagonist. |
Abbott Laboratories |
| 22197391 |
44 |
Steroidal C-21 heteroaryl thioethers (Part 2): discovery of orally bioavailable selective glucocorticoid receptor modulators (dissociated steroids). |
Merck Research Laboratories |
| 21944381 |
42 |
Steroidal C-21 mercapto derivatives as dissociated steroids: discovery of an inhaled dissociated steroid. |
Merck Research Laboratories |
| 21944856 |
51 |
Tetrahydroquinolines as a novel series of nonsteroidal selective androgen receptor modulators: structural requirements for better physicochemical and biological properties. |
Kaken Pharmaceutical |
| 21349712 |
15 |
Design and synthesis of tricyclic tetrahydroquinolines as a new series of nonsteroidal selective androgen receptor modulators (SARMs). |
Kaken Pharmaceutical |
| 15380227 |
66 |
Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands. |
University of California San Francisco |
| 12620078 |
132 |
Nonsteroidal selective glucocorticoid modulators: the effect of C-10 substitution on receptor selectivity and functional potency of 5-allyl-2,5-dihydro-2,2,4-trimethyl-1H-[1]benzopyrano[3,4-f]quinolines. |
Abbott Laboratories |
| 26546213 |
56 |
1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile. |
Corcept Therapeutics |
| 17499506 |
4 |
Synthesis and radiopharmacological characterization of [11C]AL-438 as a nonsteroidal ligand for imaging brain glucocorticoid receptors. |
Forschungszentrum Dresden-Rossendorf |
| 29424542 |
138 |
Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile. |
Astrazeneca |
| 30091920 |
113 |
Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101). |
Oric Pharmaceuticals |
| 28368581 |
82 |
Identification of the Clinical Candidate (R)-(1-(4-Fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist. |
Corcept Therapeutics |
| 28937774 |
107 |
Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases. |
Astrazeneca |
| 10908357 |
9 |
Recognition of a cognate RNA aptamer by neomycin B: quantitative evaluation of hydrogen bonding and electrostatic interactions. |
The Ohio State University |
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