The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27178386 |
1 |
Drug discovery strategies to outer membrane targets in Gram-negative pathogens. |
Astrazeneca |
12086497 |
64 |
Potent, novel in vitro inhibitors of the Pseudomonas aeruginosa deacetylase LpxC. |
Chiron |
30226381 |
16 |
Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline. |
Novartis Institutes For Biomedical Research |
28302397 |
73 |
Structure-based discovery of LpxC inhibitors. |
Cubist Pharmaceuticals |
25408833 |
21 |
Synthesis, Structure, and SAR of Tetrahydropyran-Based LpxC Inhibitors. |
Astrazeneca |
22257165 |
50 |
Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections. |
Pfizer |
22401863 |
30 |
Structure based design of an in vivo active hydroxamic acid inhibitor of P. aeruginosa LpxC. |
Pfizer |
28549219 |
30 |
Design, Synthesis, and Properties of a Potent Inhibitor of Pseudomonas aeruginosa Deacetylase LpxC. |
Novartis Institutes For Biomedical Research |
23051174 |
16 |
In vivo and in vitro effect of androstene derivatives as 5a-reductase type 1 enzyme inhibitors. |
National University of Mexico City |
15202489 |
50 |
Synthesis of hydroxy derivatives of highly potent non-steroidal CYP 17 inhibitors as potential metabolites and evaluation of their activity by a non cellular assay using recombinant human enzyme. |
Saarland University |