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12 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27816515 143 Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors.EBI Merck
27727125 24 Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators.EBI Pfizer
27490827 24 Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy.EBI Pfizer
24900695 19 Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators.EBI Chinese Academy of Sciences
31757666 314 Discovery and optimization of heteroaryl piperazines as potent and selective PI3K? inhibitors.EBI Merck
31744674 23 Design, synthesis and biological evaluation of mogrol derivatives as a novel class of AMPK?2?1?1 activators.EBI Nanjing University of Chinese Medicine
30036059 40 Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK).EBI Pfizer
29620890 25 Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations.EBI Glaxosmithkline
28345906 9 Malonylginsenosides with Potential Antidiabetic Activities from the Flower Buds of Panax ginseng.EBI Chinese Academy of Sciences
29035567 38 Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase.EBI Metabasis Therapeutics