The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27816515 |
143 |
Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors. |
Merck |
27727125 |
24 |
Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators. |
Pfizer |
27490827 |
24 |
Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy. |
Pfizer |
24900695 |
19 |
Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators. |
Chinese Academy of Sciences |
31757666 |
314 |
Discovery and optimization of heteroaryl piperazines as potent and selective PI3K? inhibitors. |
Merck |
31744674 |
23 |
Design, synthesis and biological evaluation of mogrol derivatives as a novel class of AMPK?2?1?1 activators. |
Nanjing University of Chinese Medicine |
30036059 |
40 |
Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK). |
Pfizer |
29620890 |
25 |
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations. |
Glaxosmithkline |
28345906 |
9 |
Malonylginsenosides with Potential Antidiabetic Activities from the Flower Buds of Panax ginseng. |
Chinese Academy of Sciences |
29035567 |
38 |
Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase. |
Metabasis Therapeutics |