The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28131713 |
75 |
Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics. |
Merck Research Laboratories |
| 25987375 |
20 |
Discovery of a novel Kv7 channel opener as a treatment for epilepsy. |
Pfizer |
| 25087753 |
240 |
Prediction of Thorough QT study results using action potential simulations based on ion channel screens. |
University of Oxford |
| 22793372 |
66 |
Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a potent, brain penetrant K(v)7.2 channel inhibitor. |
Vanderbilt University Medical Center |
| 24900334 |
89 |
N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy. |
TBA |
| 11356099 |
20 |
Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress. |
Abbott Laboratories |
| 11689069 |
18 |
Synthesis and activity of novel and selective I(Ks)-channel blockers. |
Aventis Pharma Deutschland |
| 31566384 |
134 |
Development of Chemical Entities Endowed with Potent Fast-Killing Properties against |
Glaxosmithkline |
| 28753313 |
45 |
Neuroactive Steroids. 2. 3?-Hydroxy-3?-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5?-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (?-Aminobutyric Acid) |
Sage Therapeutics |
Search and Browse
