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The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
29847724 25 Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase? (PI3K?) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS).EBI Vertex Pharmaceuticals