The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26745812 |
8 |
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors. |
Ludwig-Maximilians University |
23583910 |
24 |
Aminopropylindenes derived from Grundmann's ketone as a novel chemotype of oxidosqualene cyclase inhibitors. |
Ludwig-Maximilians-Universit£T M£Nchen |
17760433 |
37 |
Influence of conformation on GRIND-based three-dimensional quantitative structure-activity relationship (3D-QSAR). |
Universit£ |
17981368 |
22 |
GRIND-based 3D-QSAR to predict inhibitory activity for similar enzymes, OSC and SHC. |
Casmedchem Laboratory |
22533316 |
10 |
Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cells. |
Centre Hospitalier Universitaire Vaudois (Chuv) and University of Lausanne (Unil |
17027267 |
9 |
Design, synthesis, and biological evaluation of new (2E,6E)-10-(dimethylamino)-3,7-dimethyl-2,6-decadien-1-ol ethers as inhibitors of human and Trypanosoma cruzi oxidosqualene cyclase. |
Universit£ |
12852766 |
22 |
Synthesis and structure-activity studies of novel orally active non-terpenoic 2,3-oxidosqualene cyclase inhibitors. |
F. Hoffmann-La Roche |
22137785 |
6 |
Inhibitors of human 2,3-oxidosqualene cyclase (OSC) discovered by virtual screening. |
Institute of Microbial Chemistry |
20728352 |
5 |
Novel pyrrole- and 1,2,3-triazole-based 2,3-oxidosqualene cyclase inhibitors. |
Institute of Microbial Chemistry |
| 4 |
Inhibition of oxidosqualene cyclase by substituted quinolizidines |
TBA |
19119009 |
75 |
Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents. |
Università |
18467104 |
13 |
Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity. |
Laboratoire Glaxosmithkline |
13678402 |
12 |
Oxidosqualene cyclase inhibitors as antimicrobial agents. |
University of Utah |
12747780 |
56 |
Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase. |
Albert-Ludwigs-University of Freiburg |
11150166 |
12 |
A novel series of 4-piperidinopyridine and 4-piperidinopyrimidine inhibitors of 2,3-oxidosqualene cyclase-lanosterol synthase. |
Astrazeneca |
9484504 |
14 |
29-Methylidene-2,3-oxidosqualene derivatives as stereospecific mechanism-based inhibitors of liver and yeast oxidosqualene cyclase. |
Università |
9003518 |
23 |
Synthesis and inhibition studies of sulfur-substituted squalene oxide analogues as mechanism-based inhibitors of 2,3-oxidosqualene-lanosterol cyclase. |
Simon Fraser University |
24269162 |
84 |
NAD-based inhibitors with anticancer potential. |
University of Minnesota |
23937979 |
6 |
Discovery of N-(2,3,5-triazoyl)mycophenolic amide and mycophenolic epoxyketone as novel inhibitors of human IMPDH. |
Hokkaido University |
30322754 |
48 |
Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles. |
The University of Queensland |
29771525 |
4 |
NMR Biochemical Assay for Oxidosqualene Cyclase: Evaluation of Inhibitor Activities on Trypanosoma cruzi and Human Enzymes. |
National Institute of Advanced Industrial Science and Technology (Aist) |