The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24211162 |
55 |
Discovery of XEN445: a potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice. |
Xenon Pharmaceuticals |
23528297 |
6 |
A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice. |
Janssen Research and Development |
14711311 |
104 |
Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase. |
Novo Nordisk |
31519373 |
67 |
Benzothiazole-based compounds as potent endothelial lipase inhibitors. |
Bristol-Myers Squibb |
31176700 |
36 |
Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase. |
Bristol-Myers Squibb |
30613337 |
69 |
Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase. |
Bristol-Myers Squibb |
31990537 |
59 |
Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo. |
TBA |
30034599 |
41 |
PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor. |
Bristol-Myers Squibb |