The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26322835 |
96 |
Towards the evaluation in an animal disease model: Fluorinated 17ß-HSD1 inhibitors showing strong activity towards both the human and the rat enzyme. |
Saarland University |
24974351 |
36 |
Novel, potent and selective 17ß-hydroxysteroid dehydrogenase type 2 inhibitors as potential therapeutics for osteoporosis with dual human and mouse activities. |
Saarland University |
30645111 |
48 |
Targeted Endocrine Therapy: Design, Synthesis, and Proof-of-Principle of 17?-Hydroxysteroid Dehydrogenase Type 2 Inhibitors in Bone Fracture Healing. |
Elexopharm |
31176098 |
33 |
Development of potential preclinical candidates with promising in vitro ADME profile for the inhibition of type 1 and type 2 17?-Hydroxysteroid dehydrogenases: Design, synthesis, and biological evaluation. |
Helmholtz Institute For Pharmaceutical Research Saarland (Hips) |
31343176 |
72 |
Design, Synthesis, and Biological Characterization of Orally Active 17?-Hydroxysteroid Dehydrogenase Type 2 Inhibitors Targeting the Prevention of Osteoporosis. |
Elexopharm |
30480443 |
77 |
Highly Potent 17?-HSD2 Inhibitors with a Promising Pharmacokinetic Profile for Targeted Osteoporosis Therapy. |
Pharmbiotec |