The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
10669559 |
180 |
Protease inhibitors: current status and future prospects. |
University of Queensland |
10579821 |
51 |
Design and synthesis of thrombin inhibitors: analogues of MD-805 with reduced stereogenicity and improved potency. |
Novartis Horsham Research Centre |
10479288 |
141 |
Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa. |
Rh£Ne-Poulenc Rorer |
9301673 |
234 |
Synthesis and structure-activity relationships of potent thrombin inhibitors: piperazides of 3-amidinophenylalanine. |
Klinikum Der Friedrich-Schiller-Universit£T Jena |
8496923 |
9 |
New mechanism-based inactivators of trypsin-like proteinases. Selective inactivation of urokinase by functionalized cyclopeptides incorporating a sulfoniomethyl-substituted m-aminobenzoic acid residue. |
Cnrs-Cercoa |
15149685 |
55 |
Novel thrombin inhibitors incorporating weakly basic heterobicyclic P1-arginine mimetics: optimization via modification of P1 and P3 moieties. |
University of Ljubljana |
10560742 |
85 |
3-Amidinophenylalanine-based inhibitors of urokinase. |
UniversitäT Jena |
9784099 |
84 |
Design of benzamidine-type inhibitors of factor Xa. |
Institut FüR Biochemie |
8917639 |
50 |
Design, synthesis, and evolution of a novel, selective, and orally bioavailable class of thrombin inhibitors: P1-argininal derivatives incorporating P3-P4 lactam sulfonamide moieties. |
Corvas International |
8917638 |
26 |
Potent and selective thrombin inhibitors incorporating the constrained arginine mimic l-3-piperidyl(N-guanidino)alanine at P1. |
Corvas International |
8423602 |
15 |
Active site-directed synthetic thrombin inhibitors: synthesis, in vitro and in vivo activity profile of BMY 44621 and analogs. An examination of the role of the amino group in the D-Phe-Pro-Arg-H series. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
7932558 |
30 |
Nonpeptidic inhibitors of human leukocyte elastase. 2. Design, synthesis, and in vitro activity of a series of 3-amino-6-arylopyridin-2-one trifluoromethyl ketones. |
Zeneca Pharmaceuticals Group |
12061879 |
44 |
SMall Molecule Growth 2001 (SMoG2001): an improved knowledge-based scoring function for protein-ligand interactions. |
Harvard University |