The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26191374 |
4 |
Discovery and Characterization of a Water-Soluble Prodrug of a Dual Inhibitor of Bacterial DNA Gyrase and Topoisomerase IV. |
Vertex Pharmaceuticals |
26098163 |
66 |
Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site. |
University of Ljubljana |
23968485 |
67 |
Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity. |
Actelion Pharmaceuticals |
16392790 |
12 |
Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents. |
Achillion Pharmaceuticals |
16337791 |
34 |
Isothiazoloquinolones containing functionalized aromatic hydrocarbons at the 7-position: synthesis and in vitro activity of a series of potent antibacterial agents with diminished cytotoxicity in human cells. |
Achillion Pharmaceuticals |
16337789 |
40 |
Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus. |
Achillion Pharmaceuticals |
32027491 |
4 |
Two Decades of Successful SAR-Grounded Stories of the Novel Bacterial Topoisomerase Inhibitors (NBTIs). |
National Institute of Chemistry |
31276392 |
176 |
Virtual Screening Approach and Investigation of Structure-Activity Relationships To Discover Novel Bacterial Topoisomerase Inhibitors Targeting Gram-Positive and Gram-Negative Pathogens. |
Angelini |
31202995 |
6 |
Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: Structure-activity relationships and mode of action studies. |
Sapienza University of Rome |
24239017 |
15 |
Design, synthesis and biological evaluation of ?-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors. |
Biota Holdings |
16078842 |
6 |
A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus. |
Wockhardt |