The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24593905 |
16 |
Application of encoded library technology (ELT) to a protein-protein interaction target: discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists. |
Glaxosmithkline |
23339734 |
4 |
Design, synthesis, and functional evaluation of leukocyte function associated antigen-1 antagonists in early and late stages of cancer development. |
Ikerchem |
20655213 |
31 |
Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable LFA-1/ICAM-1 antagonists. |
Sunesis Pharmaceuticals |
20405922 |
53 |
Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521). |
Bristol-Myers Squibb Research and Development |
7852999 |
6 |
Cucurbitacins, Cell Adhesion Inhibitors from Conobea scoparioides |
TBA |
9322361 |
1 |
Four new clerodane diterpenes from the leaves of Casearia guianensis which inhibit the interaction of leukocyte function antigen 1 with intercellular adhesion molecule 1. |
Searle Research and Development |
18783948 |
31 |
Structure-activity relationship of ortho- and meta-phenol based LFA-1 ICAM inhibitors. |
Biogen Idec |
18778938 |
20 |
Design and synthesis of a series of meta aniline-based LFA-1 ICAM inhibitors. |
Biogen Idec |
11728185 |
55 |
Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 4. Structure-activity relationship of substituents on the benzene ring of the cinnamide. |
Abbott Laboratories |
12880315 |
3 |
Antiparasitic alkaloids from Psychotria klugii. |
University of Mississippi |