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23 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
24568559 7 Multitarget drug discovery for tuberculosis and other infectious diseases.EBI University of Illinois At Urbana-Champaign
22486710 3 Head-to-head prenyl tranferases: anti-infective drug targets.EBI University of Illinois At Urbana-Champaign
17371809 6 Kinetic characterization of squalene synthase from Trypanosoma cruzi: selective inhibition by quinuclidine derivatives.EBI Instituto De Parasitolog£A Y Biomedicina&Quot;L£Pez-Neyra
 10 Synthesis and biological activity of J-104,118, a novel, potent inhibitor of squalene synthaseEBI TBA
 17 The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety.EBI TBA
21576018 10 Identification of 4H,6H-[2]benzoxepino[4,5-c][1,2]oxazoles as novel squalene synthase inhibitors.EBI Bayer Pharma
21396815 20 Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors.EBI Bayer Pharma
21353782 61 Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors.EBI Daiichi Sankyo
19191557 80 Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.EBI University of Illinois At Urbana-Champaign
 5 Novel Zaragozic Acids from Leptodontidium elatiusEBI TBA
 11 Novel optimised quinuclidine squalene synthase inhibitorsEBI TBA
 10 Synthesis of triphosphonate analogues of farnesyl pyrophosphate. Inhibitors of squalene synthase and protein:farnesyl transferaseEBI TBA
 3 J-104,123, a novel and orally-active inhibitor of squalene synthase: Stereoselective synthesis and cholesterol lowering effects in dogsEBI TBA
 9 Synthesis of novel monocyclic squalestatin analogues as potential inhibitors of squalene synthaseEBI TBA
 40 Semi-synthetic qualestatins: Squalene synthase inhibition and antifungal activity. The SAR of C6 and C7 modificationsEBI TBA
19456099 37 Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.EBI University of Illinois At Urbana-Champaign
17709461 56 Quinuclidine derivatives as potential antiparasitics.EBI Cardiff University
16451055 2 Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole.EBI Instituto Venezolano De Investigaciones CientíFicas
14695831 48 Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.EBI University of Illinois At Urbana-Champaign
12238936 17 Synthesis of novel 4,1-benzoxazepine derivatives as squalene synthase inhibitors and their inhibition of cholesterol synthesis.EBI Takeda Chemical Industries
10206548 6 Novel reverse-turn mimics inhibit farnesyl transferase.EBI Cold Spring Harbor Laboratory
7966163 74 Structure-activity relationships of C1 and C6 side chains of zaragozic acid A derivatives.EBI Merck Research Laboratories
7932554 23 The squalestatins: novel inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C1-modified analogues.EBI Glaxo Research and Development