The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24568559 |
7 |
Multitarget drug discovery for tuberculosis and other infectious diseases. |
University of Illinois At Urbana-Champaign |
22486710 |
3 |
Head-to-head prenyl tranferases: anti-infective drug targets. |
University of Illinois At Urbana-Champaign |
17371809 |
6 |
Kinetic characterization of squalene synthase from Trypanosoma cruzi: selective inhibition by quinuclidine derivatives. |
Instituto De Parasitolog£A Y Biomedicina&Quot;L£Pez-Neyra |
| 10 |
Synthesis and biological activity of J-104,118, a novel, potent inhibitor of squalene synthase |
TBA |
| 17 |
The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety. |
TBA |
21576018 |
10 |
Identification of 4H,6H-[2]benzoxepino[4,5-c][1,2]oxazoles as novel squalene synthase inhibitors. |
Bayer Pharma |
21396815 |
20 |
Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors. |
Bayer Pharma |
21353782 |
61 |
Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors. |
Daiichi Sankyo |
19191557 |
80 |
Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus. |
University of Illinois At Urbana-Champaign |
| 5 |
Novel Zaragozic Acids from Leptodontidium elatius |
TBA |
| 11 |
Novel optimised quinuclidine squalene synthase inhibitors |
TBA |
| 10 |
Synthesis of triphosphonate analogues of farnesyl pyrophosphate. Inhibitors of squalene synthase and protein:farnesyl transferase |
TBA |
| 3 |
J-104,123, a novel and orally-active inhibitor of squalene synthase: Stereoselective synthesis and cholesterol lowering effects in dogs |
TBA |
| 9 |
Synthesis of novel monocyclic squalestatin analogues as potential inhibitors of squalene synthase |
TBA |
| 40 |
Semi-synthetic qualestatins: Squalene synthase inhibition and antifungal activity. The SAR of C6 and C7 modifications |
TBA |
19456099 |
37 |
Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. |
University of Illinois At Urbana-Champaign |
17709461 |
56 |
Quinuclidine derivatives as potential antiparasitics. |
Cardiff University |
16451055 |
2 |
Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. |
Instituto Venezolano De Investigaciones CientíFicas |
14695831 |
48 |
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo. |
University of Illinois At Urbana-Champaign |
12238936 |
17 |
Synthesis of novel 4,1-benzoxazepine derivatives as squalene synthase inhibitors and their inhibition of cholesterol synthesis. |
Takeda Chemical Industries |
10206548 |
6 |
Novel reverse-turn mimics inhibit farnesyl transferase. |
Cold Spring Harbor Laboratory |
7966163 |
74 |
Structure-activity relationships of C1 and C6 side chains of zaragozic acid A derivatives. |
Merck Research Laboratories |
7932554 |
23 |
The squalestatins: novel inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C1-modified analogues. |
Glaxo Research and Development |