The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
23756063 |
25 |
The discovery of potent selective NPY Y(2) antagonists. |
Janssen Research and Development |
21684740 |
44 |
Discovery of microsomal triglyceride transfer protein (MTP) inhibitors with potential for decreased active metabolite load compared to dirlotapide. |
Pfizer |
19091559 |
59 |
Identification and structure-activity relationships of ortho-biphenyl carboxamides as potent Smoothened antagonists inhibiting the Hedgehog signaling pathway. |
Novartis Institutes For Biomedical Research |
17276061 |
6 |
In vitro and in vivo profile of 5-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity. |
Pfizer |
16529928 |
72 |
Discovery of potent and orally active MTP inhibitors as potential anti-obesity agents. |
Pfizer |
15380200 |
12 |
5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
11741485 |
99 |
Diaminoindanes as microsomal triglyceride transfer protein inhibitors. |
Novartis Institute For Biomedical Reasearch |
11300866 |
14 |
A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors. |
The Bristol-Myers Squibb Pharmaceutical Research Institute |