The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
17665896 |
30 |
4-Substituted trinems as broad spectrum beta-lactamase inhibitors: structure-based design, synthesis, and biological activity. |
Lek Pharmaceuticals |
17220410 |
6 |
Use of novel boronic acid transition state inhibitors to probe substrate affinity in SHV-type extended-spectrum beta-lactamases. |
Veterans Affairs Medical Center |
8809160 |
132 |
Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases. |
F. Hoffmann-La Roche |
18316524 |
2 |
Biochemical characterization of SHV-55, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae. |
TBA |
18316518 |
4 |
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition. |
National Institute Of Health Dr. Ricardo Jorge Av. Padre Cruz |
15588091 |
25 |
Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates. |
Wyeth Research |