The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27598236 |
59 |
High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity. |
China Pharmaceutical University |
27720555 |
29 |
Structure-based design of ester compounds to inhibit MLL complex catalytic activity by targeting mixed lineage leukemia 1 (MLL1)-WDR5 interaction. |
China Pharmaceutical University |
28135235 |
71 |
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED. |
Novartis Institutes For Biomedical Research |