The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24900651 |
50 |
Irreversible inhibitors of cysteine proteases. |
Dart Neuroscience |
19715320 |
87 |
Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. |
University of Florida |
18366176 |
7 |
Identification of promiscuous small molecule activators in high-throughput enzyme activation screens. |
University of Illinois |
21903398 |
88 |
Exploiting differences in caspase-2 and -3 S2 subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. |
Chdi Management |
17181147 |
10 |
Synthesis of novel caspase inhibitors for characterization of the active caspase proteome in vitro and in vivo. |
University of Edinburgh |
15686936 |
210 |
Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors. |
Merck Frosst Centre For Therapeutic Research |
27563406 |
128 |
Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors. |
Roche Pharma Research and Early Development |
11384246 |
86 |
Potent and selective nonpeptide inhibitors of caspases 3 and 7. |
Glaxosmithkline |
16509578 |
79 |
Design, synthesis, and biological evaluation of isoquinoline-1,3,4-trione derivatives as potent caspase-3 inhibitors. |
Shanghai Institutes For Biological Sciences |
12408711 |
112 |
Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design. |
Sunesis Pharmaceuticals |