BDBM50292474 7-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylamino)heptanoic acid::Amineptin::CHEMBL418995::amineptine

SMILES: OC(=O)CCCCCCNC1c2ccccc2CCc2ccccc12

InChI Key: InChIKey=ONNOFKFOZAJDHT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pleiotropic ABC efflux transporter of multiple drugs (Saccharomyces cerevisiae S288c)	BDBM50292474 (7-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylam...) Show SMILES OC(=O)CCCCCCNC1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-21(25)13-3-1-2-8-16-23-22-19-11-6-4-9-17(19)14-15-18-10-5-7-12-20(18)22/h4-7,9-12,22-23H,1-3,8,13-16H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw Medical University Curated by ChEMBL					Assay Description Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assay				Antimicrob Agents Chemother 53: 1516-27 (2009) Article DOI: 10.1128/AAC.00956-08 BindingDB Entry DOI: 10.7270/Q2125TNZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50292474 (7-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylam...) Show SMILES OC(=O)CCCCCCNC1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C22H27NO2/c24-21(25)13-3-1-2-8-16-23-22-19-11-6-4-9-17(19)14-15-18-10-5-7-12-20(18)22/h4-7,9-12,22-23H,1-3,8,13-16H2,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometry				J Nat Prod 58: 1475-1484 (1995) Article DOI: 10.1021/np50124a001 BindingDB Entry DOI: 10.7270/Q2XK8FKW
					More data for this Ligand-Target Pair