Found 7 hits for monomerid = 50106187 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nicotinamide N-methyltransferase (NNMT)
(Homo sapiens (Human)) | BDBM50106187
(Benzenecarboxamide | Benzoic acid amide | Benzoyla...)Show InChI InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us... |
J Med Chem 62: 10783-10797 (2019)
Article DOI: 10.1021/acs.jmedchem.9b01255 |
More data for this Ligand-Target Pair | |
Coagulation factor III/Factor VIIa (fVIIa)
(Homo sapiens (Human)) | BDBM50106187
(Benzenecarboxamide | Benzoic acid amide | Benzoyla...)Show InChI InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| 4.90E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co.
Curated by ChEMBL
| Assay Description Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto... |
J Med Chem 58: 2799-808 (2015)
Article DOI: 10.1021/jm501982k BindingDB Entry DOI: 10.7270/Q28D007C |
More data for this Ligand-Target Pair | |
Coagulation factor III/Factor VIIa (fVIIa)
(Homo sapiens (Human)) | BDBM50106187
(Benzenecarboxamide | Benzoic acid amide | Benzoyla...)Show InChI InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| 4.90E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D
Curated by ChEMBL
| Assay Description Inhibition of recombinant human factor-7a/TF using S2288 as substrate measured after 60 mins |
ACS Med Chem Lett 7: 1077-1081 (2016)
Article DOI: 10.1021/acsmedchemlett.6b00282 BindingDB Entry DOI: 10.7270/Q2GB2613 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50106187
(Benzenecarboxamide | Benzoic acid amide | Benzoyla...)Show InChI InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9) | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
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Similars
| PDB Article PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description Inhibition of PARP-1 using [32P]-NAD+ after 15 mins |
J Med Chem 54: 5403-13 (2011)
Article DOI: 10.1021/jm200325s BindingDB Entry DOI: 10.7270/Q2416XFG |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
poly(ADP-ribose) glycohydrolase (PARG)
(Homo sapiens (Human)) | BDBM50106187
(Benzenecarboxamide | Benzoic acid amide | Benzoyla...)Show InChI InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description Inhibition of PARG using [alpha-32P]ADP-ribose polymers after 5 mins by TRAP assay |
J Med Chem 54: 5403-13 (2011)
Article DOI: 10.1021/jm200325s BindingDB Entry DOI: 10.7270/Q2416XFG |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50106187
(Benzenecarboxamide | Benzoic acid amide | Benzoyla...)Show InChI InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9) | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Perugia
Curated by ChEMBL
| Assay Description The compound was tested for poly(ADP-ribose)polymerase (PARP) inhibition |
J Med Chem 44: 3786-94 (2001)
BindingDB Entry DOI: 10.7270/Q2B857DN |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50106187
(Benzenecarboxamide | Benzoic acid amide | Benzoyla...)Show InChI InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9) | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc
Curated by ChEMBL
| Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1 |
J Med Chem 46: 3138-51 (2003)
Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P |
More data for this Ligand-Target Pair | 3D Structure (crystal) |