BDBM50421892 Alphatrex::BETAMETHASONE DIPROPIONATE::Diprolene::Diprolene Af::Diprosone::SCH-11460
SMILES: CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
InChI Key: InChIKey=CIWBQSYVNNPZIQ-XYWKZLDCSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucocorticoid (RAT) | BDBM50421892 (Alphatrex | BETAMETHASONE DIPROPIONATE | Diprolene...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Kasei Corporation Curated by ChEMBL | Assay Description Competitive displacement of [3H]dexamethasone from glucocorticoid receptor of rat liver cytosol | J Med Chem 34: 2468-73 (1991) BindingDB Entry DOI: 10.7270/Q2W096H9 | |||||||||||
More data for this Ligand-Target Pair |