BDBM86422 CAS_61869-08-7::NSC_43815::PAROXETINE::US9873683, Paroxetine
SMILES: Fc1ccc(cc1)C1CCNCC1COc1ccc2OCOc2c1
InChI Key: InChIKey=AHOUBRCZNHFOSL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SLC6A4 (MOUSE) | BDBM86422 (CAS_61869-08-7 | NSC_43815 | PAROXETINE | US987368...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health Curated by PDSP Ki Database | J Pharmacol Exp Ther 308: 481-6 (2004) Article DOI: 10.1124/jpet.103.058636 BindingDB Entry DOI: 10.7270/Q2QZ28J1 | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM86422 (CAS_61869-08-7 | NSC_43815 | PAROXETINE | US987368...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Tours Curated by PDSP Ki Database | J Pharmacol Exp Ther 317: 147-52 (2006) Article DOI: 10.1124/jpet.105.096792 BindingDB Entry DOI: 10.7270/Q2JW8CFZ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 4 (Homo sapiens (Human)) | BDBM86422 (CAS_61869-08-7 | NSC_43815 | PAROXETINE | US987368...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University | Assay Description The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour... | J Med Chem 51: 68-76 (2008) BindingDB Entry DOI: 10.7270/Q2MW2KFS | |||||||||||
More data for this Ligand-Target Pair |