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BDBM50156055 2-(Diphenyl-methanesulfinyl)-acetamide::2-(benzhydrylsulfinyl)acetamide::2-[(diphenylmethyl)sulfinyl]acetamide::Ambrisentan::CEP-1538::CHEMBL1373::CRL-40476::MODAFINIL::Provigil::US10913711, Compound (+-)-modafinilb::US9862679, Compound (+-)-modafinil
SMILES: NC(=O)CS(=O)C(c1ccccc1)c1ccccc1
InChI Key: InChIKey=YFGHCGITMMYXAQ-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet  | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 927 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Displacement of [3H]WIN35,428 from wild type human DAT expressed in COS7 cell membranes incubated for >90 mins by radioligand binding assay | J Med Chem 59: 10676-10691 (2016) Article DOI: 10.1021/acs.jmedchem.6b01373 BindingDB Entry DOI: 10.7270/Q2WQ05RV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Binding affinity to DAT (unknown origin) | J Med Chem 59: 10676-10691 (2016) Article DOI: 10.1021/acs.jmedchem.6b01373 BindingDB Entry DOI: 10.7270/Q2WQ05RV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | US Patent | 2.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rheinische Friedrich-Wilhelms-Universitat Bonn | Assay Description Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b... | J Med Chem 48: 7688-707 (2005) BindingDB Entry DOI: 10.7270/Q2PR7Z87 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | 2.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse - Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat brain membranes | ACS Med Chem Lett 2: 48-52 (2011) Article DOI: 10.1021/ml1002025 BindingDB Entry DOI: 10.7270/Q2PR7X07 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | US Patent | 2.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES US Patent | Assay Description Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick... | US Patent US10913711 (2021) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]WIN35,428 from Sprague-Dawley rat brain DAT after 120 mins by liquid scintillation counting analysis | J Med Chem 57: 1000-13 (2014) Article DOI: 10.1021/jm401754x BindingDB Entry DOI: 10.7270/Q2JM2DMK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 3.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to human DAT A480T mutant expressed in African green monkey COS7 cells assessed as inhibition of [3H]-dopamine uptake after 5 mins b... | J Med Chem 57: 1000-13 (2014) Article DOI: 10.1021/jm401754x BindingDB Entry DOI: 10.7270/Q2JM2DMK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Acenta Discovery, Inc. Curated by ChEMBL | Assay Description Inhibition of high affinity uptake by the dopamine transporter from rat synaptosomal nerve endings by using [3H]DA as radioligand | J Med Chem 47: 5821-4 (2004) Article DOI: 10.1021/jm040117o BindingDB Entry DOI: 10.7270/Q2Q81DVF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | PubMed | 8.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatum membranes incubated for 120 mins by microbeta scintillation counting method | J Med Chem 63: 2343-2357 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Norepinephrine Monoamine transporters (Rattus norvegicus) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Acenta Discovery, Inc. Curated by ChEMBL | Assay Description Inhibition of high affinity uptake by the norepinephrine transporter from rat synaptosomal nerve endings by using [3H]NE as radioligand | J Med Chem 47: 5821-4 (2004) Article DOI: 10.1021/jm040117o BindingDB Entry DOI: 10.7270/Q2Q81DVF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to wild type human DAT expressed in African green monkey COS7 cells assessed as inhibition of [3H]-dopamine uptake after 5 mins by b... | J Med Chem 57: 1000-13 (2014) Article DOI: 10.1021/jm401754x BindingDB Entry DOI: 10.7270/Q2JM2DMK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | PubMed | 3.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from SERT in Sprague-Dawley rat midbrain membranes incubated for 60 mins by microbeta scintillation counting method | J Med Chem 63: 2343-2357 (2020) | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | 5.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to human SERT T497A mutant expressed in African green monkey COS7 cells assessed as inhibition of [3H]-serotonin uptake after 3 mins... | J Med Chem 57: 1000-13 (2014) Article DOI: 10.1021/jm401754x BindingDB Entry DOI: 10.7270/Q2JM2DMK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocon Bristol-Myers Squibb R&D Centre Curated by ChEMBL | Assay Description Inhibition of rat brain DAT assessed as reduction of [3H]-DA re-uptake preincubated for 30 mins followed by [3H]-DA addition measured after 5 mins by... | J Med Chem 61: 2133-2165 (2018) Article DOI: 10.1021/acs.jmedchem.6b01827 BindingDB Entry DOI: 10.7270/Q2BV7K8M | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biocon Bristol-Myers Squibb R&D Centre Curated by ChEMBL | Assay Description Inhibition of rat brain NET assessed as reduction of [3H]-NE re-uptake preincubated for 30 mins followed by [3H]-NE addition measured after 5 mins by... | J Med Chem 61: 2133-2165 (2018) Article DOI: 10.1021/acs.jmedchem.6b01827 BindingDB Entry DOI: 10.7270/Q2BV7K8M | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.84E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna Curated by ChEMBL | Assay Description Inhibition of re-uptake of [3H]MPP+ at human NET expressed in HEK293 cells preincubated for 5 mins followed by [3H]-dopamine addition measured after ... | J Med Chem 60: 9330-9348 (2017) Article DOI: 10.1021/acs.jmedchem.7b01313 BindingDB Entry DOI: 10.7270/Q26112RW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Vienna Curated by ChEMBL | Assay Description Inhibition of re-uptake of [3H]-dopamine at human DAT expressed in HEK293 cells preincubated for 5 mins followed by [3H]-dopamine addition measured a... | J Med Chem 60: 9330-9348 (2017) Article DOI: 10.1021/acs.jmedchem.7b01313 BindingDB Entry DOI: 10.7270/Q26112RW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon (France) Curated by ChEMBL | Assay Description Inhibition of CYP2C19 | Eur J Med Chem 54: 949-51 (2012) Article DOI: 10.1016/j.ejmech.2012.05.038 BindingDB Entry DOI: 10.7270/Q2833T23 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon (France) Curated by ChEMBL | Assay Description Inhibition of rat SERT-mediated serotonin reuptake | Eur J Med Chem 54: 949-51 (2012) Article DOI: 10.1016/j.ejmech.2012.05.038 BindingDB Entry DOI: 10.7270/Q2833T23 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon (France) Curated by ChEMBL | Assay Description Inhibition of rat NET-mediated norepinephrine reuptake | Eur J Med Chem 54: 949-51 (2012) Article DOI: 10.1016/j.ejmech.2012.05.038 BindingDB Entry DOI: 10.7270/Q2833T23 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon (France) Curated by ChEMBL | Assay Description Inhibition of rat DAT-mediated dopamine reuptake | Eur J Med Chem 54: 949-51 (2012) Article DOI: 10.1016/j.ejmech.2012.05.038 BindingDB Entry DOI: 10.7270/Q2833T23 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon (France) Curated by ChEMBL | Assay Description Inhibition of rat DAT | Eur J Med Chem 54: 949-51 (2012) Article DOI: 10.1016/j.ejmech.2012.05.038 BindingDB Entry DOI: 10.7270/Q2833T23 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Displacement of 3H-WIN-35428 from DAT in rat striata after 120 mins | Bioorg Med Chem Lett 22: 3751-3 (2012) Article DOI: 10.1016/j.bmcl.2012.04.031 BindingDB Entry DOI: 10.7270/Q2N29XZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of CYP2C19 | Bioorg Med Chem Lett 22: 3751-3 (2012) Article DOI: 10.1016/j.bmcl.2012.04.031 BindingDB Entry DOI: 10.7270/Q2N29XZB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of rat DAT | Bioorg Med Chem Lett 22: 2312-4 (2012) Article DOI: 10.1016/j.bmcl.2011.12.099 BindingDB Entry DOI: 10.7270/Q2765FTW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of rat DAT-mediated dopamine reuptake | Bioorg Med Chem Lett 22: 2312-4 (2012) Article DOI: 10.1016/j.bmcl.2011.12.099 BindingDB Entry DOI: 10.7270/Q2765FTW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of rat NET-mediated norepinephrine reuptake | Bioorg Med Chem Lett 22: 2312-4 (2012) Article DOI: 10.1016/j.bmcl.2011.12.099 BindingDB Entry DOI: 10.7270/Q2765FTW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of CYP2C19 | Bioorg Med Chem Lett 22: 2312-4 (2012) Article DOI: 10.1016/j.bmcl.2011.12.099 BindingDB Entry DOI: 10.7270/Q2765FTW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50156055 (2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inhibition of rat SERT-mediated serotonin reuptake | Bioorg Med Chem Lett 22: 2312-4 (2012) Article DOI: 10.1016/j.bmcl.2011.12.099 BindingDB Entry DOI: 10.7270/Q2765FTW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
