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BDBM50128572 1-Naphthalenol, methylcarbamate::1-Naphthalenyl methylcarbamate::1-Naphthyl N-methylcarbamate::CHEMBL46917::Carbaril::Carbaryl::N-Methyl-1-naphthyl carbamate::N-Methyl-alpha-naphthylurethan::Sevin::alpha-Naphthyl N-methylcarbamate::cid_6129::naphthalen-1-yl methylcarbamate

SMILES: CNC(=O)Oc1cccc2ccccc12

InChI Key: InChIKey=CVXBEEMKQHEXEN-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50128572   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein 5


(Homo sapiens (Human))
BDBM50128572
PNG
(1-Naphthalenol, methylcarbamate | 1-Naphthalenyl m...)
Show SMILES CNC(=O)Oc1cccc2ccccc12
Show InChI InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
PDB
MMDB

KEGG

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PCBioAssay
n/an/a 5.00E+4n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2GH9GC8
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Electrophorus electricus (Electric eel))
BDBM50128572
PNG
(1-Naphthalenol, methylcarbamate | 1-Naphthalenyl m...)
Show SMILES CNC(=O)Oc1cccc2ccccc12
Show InChI InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
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MCE
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Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Università degli Studi di Urbino Carlo Bo

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound towards eel acetylcholinesterase(AchE)


J Med Chem 46: 2352-60 (2003)


Article DOI: 10.1021/jm021119g
BindingDB Entry DOI: 10.7270/Q2DB817C
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50128572
PNG
(1-Naphthalenol, methylcarbamate | 1-Naphthalenyl m...)
Show SMILES CNC(=O)Oc1cccc2ccccc12
Show InChI InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human FAAH


J Med Chem 51: 7327-43 (2009)


Article DOI: 10.1021/jm800311k
BindingDB Entry DOI: 10.7270/Q2J67HT8
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Bos taurus (bovine))
BDBM50128572
PNG
(1-Naphthalenol, methylcarbamate | 1-Naphthalenyl m...)
Show SMILES CNC(=O)Oc1cccc2ccccc12
Show InChI InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
PDB
MMDB

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Article
n/an/a 5.74E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of bovine erythrocyte acetylcholinesterase (AChE)


Bioorg Med Chem Lett 6: 77-80 (1996)


Article DOI: 10.1016/0960-894X(95)00562-8
BindingDB Entry DOI: 10.7270/Q27W6C5T
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50128572
PNG
(1-Naphthalenol, methylcarbamate | 1-Naphthalenyl m...)
Show SMILES CNC(=O)Oc1cccc2ccccc12
Show InChI InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of FAAH


Bioorg Med Chem Lett 21: 4674-85 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.096
BindingDB Entry DOI: 10.7270/Q2W959JK
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579)


(Rattus norvegicus (rat))
BDBM50128572
PNG
(1-Naphthalenol, methylcarbamate | 1-Naphthalenyl m...)
Show SMILES CNC(=O)Oc1cccc2ccccc12
Show InChI InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)
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CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Università degli Studi di Urbino Carlo Bo

Curated by ChEMBL


Assay Description
Fatty acid amide hydrolase inhibitory activity in rat brain membrane using [3H]-anandamide as a substrate


J Med Chem 46: 2352-60 (2003)


Article DOI: 10.1021/jm021119g
BindingDB Entry DOI: 10.7270/Q2DB817C
More data for this
Ligand-Target Pair