BDBM50200099 2-Amino-1,7-dihydro-purine-6-thione::2-Amino-1,9-dihydro-purine-6-thione::2-Amino-9H-purine-6-thiol::2-amino-1,9-dihydro-6H-purine-6-thione::2-amino-1H-purine-6(7H)-thione::2-amino-1H-purine-6(9H)-thione::6-thioguanine::CHEMBL727::THIOGUANINE::Thioquanine::Tioguanine

SMILES: Nc1nc2nc[nH]c2c(=S)[nH]1

InChI Key: InChIKey=WYWHKKSPHMUBEB-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (Escherichia coli (strain K12))	BDBM50200099 (2-Amino-1,7-dihydro-purine-6-thione | 2-Amino-1,9-...) Show SMILES Nc1nc2nc[nH]c2c(=S)[nH]1 Show InChI InChI=1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Binding affinity to GST-tagged Escherichia coli HPPK expressed in Escherichia coli by SPR assay based alternative equilibrium affinity method in pres...				Bioorg Med Chem 22: 2157-65 (2014) Article DOI: 10.1016/j.bmc.2014.02.022 BindingDB Entry DOI: 10.7270/Q2ST7SSH
					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM50200099 (2-Amino-1,7-dihydro-purine-6-thione | 2-Amino-1,9-...) Show SMILES Nc1nc2nc[nH]c2c(=S)[nH]1 Show InChI InChI=1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Biological Chemistry and the Genomics Research Center Curated by ChEMBL					Assay Description Inhibition of human xanthine oxidase				Bioorg Med Chem 15: 3450-6 (2007) Article DOI: 10.1016/j.bmc.2007.03.010 BindingDB Entry DOI: 10.7270/Q2WD407G
					More data for this Ligand-Target Pair