BDBM50017041 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline::1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline::1BnTIQ::CHEMBL21640::rac-(1R)-1-benzyl-1,2,3,4-tetrahydroisoquinoline

SMILES: C(C1NCCc2ccccc12)c1ccccc1

InChI Key: InChIKey=YRYCIFUZSUMAAY-UHFFFAOYSA-N

Data: 3 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50017041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50017041 ((RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline | 1,2...) Show SMILES C(C1NCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H17N/c1-2-6-13(7-3-1)12-16-15-9-5-4-8-14(15)10-11-17-16/h1-9,16-17H,10-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description The compound has been evaluated for its binding affinity towards Dopamine receptor D2 by displacing the radioligand [3H]-YM-09151-2 (0.5 nM) in rat s...				Bioorg Med Chem Lett 10: 1669-71 (2000) BindingDB Entry DOI: 10.7270/Q2M61JH0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50017041 ((RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline | 1,2...) Show SMILES C(C1NCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H17N/c1-2-6-13(7-3-1)12-16-15-9-5-4-8-14(15)10-11-17-16/h1-9,16-17H,10-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.66E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description The compound has been evaluated for its binding affinity towards Dopamine transporter by displacing the radioligand [3H]-GBR-12,935 (1.0 nM) in rat s...				Bioorg Med Chem Lett 10: 1669-71 (2000) BindingDB Entry DOI: 10.7270/Q2M61JH0
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50017041 ((RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline | 1,2...) Show SMILES C(C1NCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H17N/c1-2-6-13(7-3-1)12-16-15-9-5-4-8-14(15)10-11-17-16/h1-9,16-17H,10-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	2.49E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Tokyo Curated by ChEMBL					Assay Description The compound has been evaluated for its binding affinity towards Dopamine receptor D1 by displacing the radioligand [3H]-SCH-23,390 (1.5 nM) in rat s...				Bioorg Med Chem Lett 10: 1669-71 (2000) BindingDB Entry DOI: 10.7270/Q2M61JH0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50017041 ((RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline | 1,2...) Show SMILES C(C1NCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H17N/c1-2-6-13(7-3-1)12-16-15-9-5-4-8-14(15)10-11-17-16/h1-9,16-17H,10-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
					More data for this Ligand-Target Pair
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50017041 ((RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline | 1,2...) Show SMILES C(C1NCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H17N/c1-2-6-13(7-3-1)12-16-15-9-5-4-8-14(15)10-11-17-16/h1-9,16-17H,10-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle& Co. Curated by ChEMBL					Assay Description Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptor				J Med Chem 32: 1242-8 (1989) BindingDB Entry DOI: 10.7270/Q2CR5TXJ
					More data for this Ligand-Target Pair
Adrenergic Alpha (Homo sapiens (Human))	BDBM50017041 ((RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline | 1,2...) Show SMILES C(C1NCCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C16H17N/c1-2-6-13(7-3-1)12-16-15-9-5-4-8-14(15)10-11-17-16/h1-9,16-17H,10-12H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of MPP+ after 1 min				J Med Chem 60: 2685-2696 (2017) Article DOI: 10.1021/acs.jmedchem.6b01317 BindingDB Entry DOI: 10.7270/Q2NV9MHQ
					More data for this Ligand-Target Pair