BDBM21242 (2S,3S,4R,5R)-5-(6-{[(4-aminophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxy-N-methyloxolane-2-carboxamide::AB-MECA::N(6)-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide::[3H]AB-MECA
SMILES: CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3ccc(N)cc3)ncnc12
InChI Key: InChIKey=LDYMCRRFCMRFKB-MOROJQBDSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A2a and A3 (Rattus norvegicus) | BDBM21242![]() ((2S,3S,4R,5R)-5-(6-{[(4-aminophenyl)methyl]amino}-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity for rat A3-adenosine receptor expressed in chinese hamster ovarian cells (assayed by the displacement of specific [125I]-N6-(4-amino... | J Med Chem 37: 636-46 (1994) BindingDB Entry DOI: 10.7270/Q2057GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM21242![]() ((2S,3S,4R,5R)-5-(6-{[(4-aminophenyl)methyl]amino}-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara Curated by PDSP Ki Database | Mol Pharmacol 57: 968-75 (2000) BindingDB Entry DOI: 10.7270/Q2CJ8C1K | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM21242![]() ((2S,3S,4R,5R)-5-(6-{[(4-aminophenyl)methyl]amino}-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | 21.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universität Würzburg Curated by PDSP Ki Database | Naunyn Schmiedebergs Arch Pharmacol 357: 1-9 (1998) Article DOI: 10.1007/pl00005131 BindingDB Entry DOI: 10.7270/Q20Z71T3 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM21242![]() ((2S,3S,4R,5R)-5-(6-{[(4-aminophenyl)methyl]amino}-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | PubMed | 431 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Binding affinity for A1-adenosine receptor by the displacement of specific [3H]-PIA binding in rat brain was determined | J Med Chem 37: 636-46 (1994) BindingDB Entry DOI: 10.7270/Q2057GJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM21242![]() ((2S,3S,4R,5R)-5-(6-{[(4-aminophenyl)methyl]amino}-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | PubMed | 435 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara Curated by PDSP Ki Database | Mol Pharmacol 57: 968-75 (2000) BindingDB Entry DOI: 10.7270/Q2CJ8C1K | ||||||||||||
More data for this Ligand-Target Pair |