BDBM50076394 2-Amino-bicyclo[2.2.1]heptane-2,7-dicarboxylic acid::ABHD-I::CHEMBL39215

SMILES: NC1(CC2CCC1C2C(O)=O)C(O)=O

InChI Key: InChIKey=FWDRMAAPXRQEDA-UHFFFAOYSA-N

Data: 1 KI  2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50076394 (2-Amino-bicyclo[2.2.1]heptane-2,7-dicarboxylic aci...) Show SMILES NC1(CC2CCC1C2C(O)=O)C(O)=O |TLB:0:1:7:5.4,THB:11:1:7:5.4,8:7:1.2:5.4| Show InChI InChI=1S/C9H13NO4/c10-9(8(13)14)3-4-1-2-5(9)6(4)7(11)12/h4-6H,1-3,10H2,(H,11,12)(H,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP Ki Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (RAT)	BDBM50076394 (2-Amino-bicyclo[2.2.1]heptane-2,7-dicarboxylic aci...) Show SMILES NC1(CC2CCC1C2C(O)=O)C(O)=O |TLB:0:1:7:5.4,THB:11:1:7:5.4,8:7:1.2:5.4| Show InChI InChI=1S/C9H13NO4/c10-9(8(13)14)3-4-1-2-5(9)6(4)7(11)12/h4-6H,1-3,10H2,(H,11,12)(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Parc Club Orsay Université Curated by ChEMBL					Assay Description Inhibitory activity of the compound against Metabotropic glutamate receptor 1 in the rat LLC-PK1/HEK 293 cells.				J Med Chem 42: 1546-55 (1999) Article DOI: 10.1021/jm980571q BindingDB Entry DOI: 10.7270/Q27H1HRD
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50076394 (2-Amino-bicyclo[2.2.1]heptane-2,7-dicarboxylic aci...) Show SMILES NC1(CC2CCC1C2C(O)=O)C(O)=O |TLB:0:1:7:5.4,THB:11:1:7:5.4,8:7:1.2:5.4| Show InChI InChI=1S/C9H13NO4/c10-9(8(13)14)3-4-1-2-5(9)6(4)7(11)12/h4-6H,1-3,10H2,(H,11,12)(H,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibitory binding activity towards metabotropic glutamate receptor (mGluRla) expressed in LLC-PK1 cells				Bioorg Med Chem Lett 5: 2627-2632 (1995) Article DOI: 10.1016/0960-894X(95)00457-5 BindingDB Entry DOI: 10.7270/Q27944NK
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50076394 (2-Amino-bicyclo[2.2.1]heptane-2,7-dicarboxylic aci...) Show SMILES NC1(CC2CCC1C2C(O)=O)C(O)=O |TLB:0:1:7:5.4,THB:11:1:7:5.4,8:7:1.2:5.4| Show InChI InChI=1S/C9H13NO4/c10-9(8(13)14)3-4-1-2-5(9)6(4)7(11)12/h4-6H,1-3,10H2,(H,11,12)(H,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the 1S,3R-ACPD stimulation of IP formation by the compound in LLC-PK1 cells expressing Metabotropic glutamate receptor (mGluRla)				Bioorg Med Chem Lett 5: 2627-2632 (1995) Article DOI: 10.1016/0960-894X(95)00457-5 BindingDB Entry DOI: 10.7270/Q27944NK
					More data for this Ligand-Target Pair