BDBM100654 US8507676, 3

SMILES: C\C(=N/OCCO)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1

InChI Key: InChIKey=OOOQQBXVJMGTTP-DHRITJCHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100654 (US8507676, 3) Show SMILES C\C(=N/OCCO)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 Show InChI InChI=1S/C20H18FN5O2/c1-13(25-28-8-7-27)18-4-5-20-23-12-16(26(20)24-18)10-15-9-14-3-2-6-22-19(14)11-17(15)21/h2-6,9,11-12,27H,7-8,10H2,1H3/b25-13+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair