BDBM100660 US8507676, 9

SMILES: C\C(=N/OCCO)c1ccc2ncc(Cc3c(F)cc4ncccc4c3F)n2n1

InChI Key: InChIKey=KJZCMRGSXUDMRS-RPPGKUMJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100660 (US8507676, 9) Show SMILES C\C(=N/OCCO)c1ccc2ncc(Cc3c(F)cc4ncccc4c3F)n2n1 Show InChI InChI=1S/C20H17F2N5O2/c1-12(26-29-8-7-28)17-4-5-19-24-11-13(27(19)25-17)9-15-16(21)10-18-14(20(15)22)3-2-6-23-18/h2-6,10-11,28H,7-9H2,1H3/b26-12+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair