BDBM100663 US8507676, 12-S

SMILES: C[C@H](c1cnc2ccc(nn12)C(\C)=N\OCCO)c1c(F)cc2ncccc2c1F

InChI Key: InChIKey=XOSSPXPZHOYILG-VEHWCJERSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100663 (US8507676, 12-S) Show SMILES C[C@H](c1cnc2ccc(nn12)C(\C)=N\OCCO)c1c(F)cc2ncccc2c1F |r| Show InChI InChI=1S/C21H19F2N5O2/c1-12(20-15(22)10-17-14(21(20)23)4-3-7-24-17)18-11-25-19-6-5-16(26-28(18)19)13(2)27-30-9-8-29/h3-7,10-12,29H,8-9H2,1-2H3/b27-13+/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair