BDBM100670 US8507676, 19

SMILES: C\C(=N/O[C@H]1CCNC1)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1

InChI Key: InChIKey=ZGPIDUWSADXAIJ-OJMOCAQPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100670 (US8507676, 19) Show SMILES C\C(=N/O[C@H]1CCNC1)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 |r| Show InChI InChI=1S/C20H19FN8O/c1-12(27-30-15-4-6-22-9-15)18-10-24-19-20(25-18)29(28-26-19)11-14-7-13-3-2-5-23-17(13)8-16(14)21/h2-3,5,7-8,10,15,22H,4,6,9,11H2,1H3/b27-12+/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair