BDBM100689 US8507676, 37A

SMILES: COC(=O)NCCO\N=C(/C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1

InChI Key: InChIKey=MLJLRCOGNFZSIE-LGJNPRDNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100689 (US8507676, 37A) Show SMILES COC(=O)NCCO\N=C(/C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 Show InChI InChI=1S/C20H20N8O3/c1-13(26-31-9-8-22-20(29)30-2)17-11-23-18-19(24-17)28(27-25-18)12-14-5-6-16-15(10-14)4-3-7-21-16/h3-7,10-11H,8-9,12H2,1-2H3,(H,22,29)/b26-13+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair