BDBM100715 US8507676, 64

SMILES: COCCO\N=C(/C)c1ccc2nnc(C(C)c3c(F)cc4ncccc4c3F)n2n1

InChI Key: InChIKey=TYELNEXHOJMZBY-XODNFHPESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100715 (US8507676, 64) Show SMILES COCCO\N=C(/C)c1ccc2nnc(C(C)c3c(F)cc4ncccc4c3F)n2n1 Show InChI InChI=1S/C21H20F2N6O2/c1-12(19-15(22)11-17-14(20(19)23)5-4-8-24-17)21-26-25-18-7-6-16(27-29(18)21)13(2)28-31-10-9-30-3/h4-8,11-12H,9-10H2,1-3H3/b28-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair