BDBM100719 US8507676, 68-R::US8507676, 68-S

SMILES: CC(c1nnc2ccc(nn12)C(\C)=N\OCC(O)=O)c1c(F)cc2ncccc2c1F

InChI Key: InChIKey=DAUMKQSIGKVWOT-LUOAPIJWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100719 (US8507676, 68-R | US8507676, 68-S) Show SMILES CC(c1nnc2ccc(nn12)C(\C)=N\OCC(O)=O)c1c(F)cc2ncccc2c1F Show InChI InChI=1S/C20H16F2N6O3/c1-10(18-13(21)8-15-12(19(18)22)4-3-7-23-15)20-25-24-16-6-5-14(26-28(16)20)11(2)27-31-9-17(29)30/h3-8,10H,9H2,1-2H3,(H,29,30)/b27-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100719 (US8507676, 68-R | US8507676, 68-S) Show SMILES CC(c1nnc2ccc(nn12)C(\C)=N\OCC(O)=O)c1c(F)cc2ncccc2c1F Show InChI InChI=1S/C20H16F2N6O3/c1-10(18-13(21)8-15-12(19(18)22)4-3-7-23-15)20-25-24-16-6-5-14(26-28(16)20)11(2)27-31-9-17(29)30/h3-8,10H,9H2,1-2H3,(H,29,30)/b27-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair