BDBM100729 US8507676, 79

SMILES: C\C(=N/OCCO)c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1

InChI Key: InChIKey=LQGWMOIBTKHFFX-ZMOGYAJESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100729 (US8507676, 79) Show SMILES C\C(=N/OCCO)c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C19H18N6O2/c1-13(24-27-8-7-26)18-12-22-19-21-11-16(25(19)23-18)10-14-4-5-17-15(9-14)3-2-6-20-17/h2-6,9,11-12,26H,7-8,10H2,1H3/b24-13+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair