BDBM100927 US8524909, 115::US8524909, 12::US8524909, 44

SMILES: FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCCC2)c(c1)C1CC1

InChI Key: InChIKey=SFCADRZKHYKTKL-RTBURBONSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Bos taurus (Bovine))	BDBM100927 (US8524909, 115 | US8524909, 12 | US8524909, 44) Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C21H27F3N2O2/c22-21(23,24)14-7-8-16(17(11-14)13-5-6-13)20(27)26-19-12-28-10-9-18(19)25-15-3-1-2-4-15/h7-8,11,13,15,18-19,25H,1-6,9-10,12H2,(H,26,27)/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	299	n/a	n/a	n/a	n/a	n/a	0
Hoffmann-La Roche Inc. US Patent					Assay Description Glycine uptake inhibition assay.				US Patent US8524909 (2013) BindingDB Entry DOI: 10.7270/Q2QJ7FXS
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Bos taurus (Bovine))	BDBM100927 (US8524909, 115 | US8524909, 12 | US8524909, 44) Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CCCC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C21H27F3N2O2/c22-21(23,24)14-7-8-16(17(11-14)13-5-6-13)20(27)26-19-12-28-10-9-18(19)25-15-3-1-2-4-15/h7-8,11,13,15,18-19,25H,1-6,9-10,12H2,(H,26,27)/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	0
Hoffmann-La Roche Inc. US Patent					Assay Description Glycine uptake inhibition assay.				US Patent US8524909 (2013) BindingDB Entry DOI: 10.7270/Q2QJ7FXS
					More data for this Ligand-Target Pair