BDBM100933 US8524909, 18

SMILES: FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NCC2CC2)c(c1)C1CC1

InChI Key: InChIKey=FXLSNYFAAAKPND-QZTJIDSGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1b (Bos taurus (Bovine))	BDBM100933 (US8524909, 18) Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NCC2CC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C20H25F3N2O2/c21-20(22,23)14-5-6-15(16(9-14)13-3-4-13)19(26)25-18-11-27-8-7-17(18)24-10-12-1-2-12/h5-6,9,12-13,17-18,24H,1-4,7-8,10-11H2,(H,25,26)/t17-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	0
Hoffmann-La Roche Inc. US Patent					Assay Description Glycine uptake inhibition assay.				US Patent US8524909 (2013) BindingDB Entry DOI: 10.7270/Q2QJ7FXS
					More data for this Ligand-Target Pair