BDBM100935 US8524909, 20

SMILES: FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CC2)c(c1)C1CC1

InChI Key: InChIKey=BHLLCWVSTKBYLS-IAGOWNOFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Bos taurus (Bovine))	BDBM100935 (US8524909, 20) Show SMILES FC(F)(F)c1ccc(C(=O)N[C@@H]2COCC[C@H]2NC2CC2)c(c1)C1CC1 |r| Show InChI InChI=1S/C19H23F3N2O2/c20-19(21,22)12-3-6-14(15(9-12)11-1-2-11)18(25)24-17-10-26-8-7-16(17)23-13-4-5-13/h3,6,9,11,13,16-17,23H,1-2,4-5,7-8,10H2,(H,24,25)/t16-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	194	n/a	n/a	n/a	n/a	n/a	0
Hoffmann-La Roche Inc. US Patent					Assay Description Glycine uptake inhibition assay.				US Patent US8524909 (2013) BindingDB Entry DOI: 10.7270/Q2QJ7FXS
					More data for this Ligand-Target Pair