BDBM100937 US8524909, 125::US8524909, 22

SMILES: COc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F

InChI Key: InChIKey=PLTVTYLSBCWJSJ-HUUCEWRRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 100937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Bos taurus (Bovine))	BDBM100937 (US8524909, 125 | US8524909, 22) Show SMILES COc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3/c1-12-9-13(19(20,21)22)10-16(26-2)17(12)18(25)23-14-11-27-8-5-15(14)24-6-3-4-7-24/h9-10,14-15H,3-8,11H2,1-2H3,(H,23,25)/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	33.8	n/a	n/a	n/a	n/a	n/a	0
Hoffmann-La Roche Inc. US Patent					Assay Description Glycine uptake inhibition assay.				US Patent US8524909 (2013) BindingDB Entry DOI: 10.7270/Q2QJ7FXS
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent glycine transporter 1 (Bos taurus (Bovine))	BDBM100937 (US8524909, 125 | US8524909, 22) Show SMILES COc1cc(cc(C)c1C(=O)N[C@@H]1COCC[C@H]1N1CCCC1)C(F)(F)F |r| Show InChI InChI=1S/C19H25F3N2O3/c1-12-9-13(19(20,21)22)10-16(26-2)17(12)18(25)23-14-11-27-8-5-15(14)24-6-3-4-7-24/h9-10,14-15H,3-8,11H2,1-2H3,(H,23,25)/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	0
Hoffmann-La Roche Inc. US Patent					Assay Description Glycine uptake inhibition assay.				US Patent US8524909 (2013) BindingDB Entry DOI: 10.7270/Q2QJ7FXS
					More data for this Ligand-Target Pair